بررسی میزان روی سرم در مبتلایان به دیابت بارداری: یک مطالعه مقایسهای در بیمارستان میرزا کوچکخان
Authors
Abstract:
Background: Maternal zinc deficiency during pregnancy has been related to adverse pregnancy outcomes. Most studies in which pregnant women have been supplemented with zinc to examine its effects on the outcome of the pregnancy have been carried out in industrialized countries and the results have been inconclusive. It has been shown that women with gestational diabetes (GDM) have lower serum zinc levels than healthy pregnant women, and higher rates of macrosomia. Zinc is required for normal glucose metabolism, and strengthens the insulin-induced transportation of glucose into cells by its effect on the insulin signaling pathway. The purpose of this study was to assess the serum zinc levels of GDM patients and evaluate the effect of zinc supplementation. Methods: In the first stage of this prospective controlled study, we enrolled 70 women who were 24-28 weeks pregnant at the Prenatal Care Center of Mirza Kochak Khan Hospital, Tehran, Iran. The serum zinc level of each subject was determined. In the second stage, among these 70 subjects, the diabetics receiving insulin were divided into two groups, only one of which received a zinc supplement and the other group was the control group. Birth weight of neonates and insulin dosages were recorded.Results: The mean serum zinc level in the GDM group was lower than that of the control group (94.83 vs. 103.49mg/dl, respectively) and the mean birth weight of neonates from the GDM women who received the zinc supplement was lower than that of the control group (3849g vs. 4136g). The rate of macrosomia was lower in the zinc supplemented group (20% vs. 53%). The mean of increase of insulin after receiving the zinc supplement was lower (8.4u vs. 13.53). Conclusion: Maternal insulin resistance is associated with the accumulation of maternal fat tissue during early stages of pregnancy and greater fetoplacental nutrient availability in later stages, when 70% of fetal growth occurs, resulting in macrosomia. In our study, zinc supplementation is associated with a reduction in the rate of fetal macrosomia among pregnant women with GDM.
similar resources
سطح هموسیستیین سرم در دیابت بارداری: یک مطالعه آیندهنگر
Normal 0 false false false EN-US X-NONE AR-SA MicrosoftInternetExplorer4 /* Style Definitions */ table.MsoNormalTable {mso-style-name:"Table Normal" mso-tsty...
full textمقایسه میزان غلظت هموگلوبین و ذخایر آهن سرم در زنان باردار سالم و مبتلایان به دیابت بارداری
سابقه و هدف: دیابت بارداری یکی از شایع ترین مشکلات بهداشتی در بارداری محسوب می شود که می تواند منجر به دیابت نوع 2 ایجاد ناتوانی و مرگ و میر و عوارض بلند مدت شود. از آنجائیکه برخی مطالعات بالا بودن هموگلوبین مادر و ذخیره آهن بدن را یک عامل خطر غیر وابسته برای دیابت بارداری می دانند. این مطالعه به منظور مقایسه میزان غلظت هموگلوبین و ذخایر آهن سرم در زنان باردار سالم با زنان مبتلا به دیابت باردار...
full textبررسی میزان سطوح سرمی هموسیستئین، آدیپونکتین و اسید اوریک در مبتلایان به دیابت بارداری در مقایسه با بارداری سالم
مقدمه: اطلاعات کم و ضدونقیضی در رابطه با ارتباط سطوح سرمی هموسیستئین، نسبت آدیپونکتین به هموسیستئین و اسید اوریک با شاخصهای مقاومت به انسولین در دیابت بارداری گزارش شده است. لذا مطالعه حاضر با هدف بررسی سطوح سرمی هموسیستئین، آدیپونکتین، نسبت آدیپونکتین به هموسیستئین و اسید اوریک و ارتباط آنها با شاخصهای مقاومت به انسولین در دیابت بارداری در مقایسه با بارداری سالم انجام شد. روشکار: این مطا...
full textمقایسه میزان هموگلوبین و میانگین حجم سلولی سرم در مادران سالم و مبتلا به دیابت بارداری
Background & Aim: Screening methods of gestational diabetes mellitus (GDM) diagnosis is controversy. The survey of relation between GDM and its risk factors helps to determine screening methods. This study was performed to find weather the prevalence of gestational diabetes mellitus (GDM) is influenced by higher hemoglobin (Hb) level and mean corpuscular volume (MCV) before 14 weeks gestation i...
full textاثر بربرین در تنظیم آستروسیتهای Gfap+ ناحیه هیپوکمپ موشهای صحرایی دیابتی شده با استرپتوزوتوسین
Background: Diabetes mellitus increases the risk of central nervous system (CNS) disorders such as stroke, seizures, dementia, and cognitive impairment. Berberine, a natural isoquinolne alkaloid, is reported to exhibit beneficial effect in various neurodegenerative and neuropsychiatric disorders. Moreover astrocytes are proving critical for normal CNS function, and alterations in their activity...
full textاثر بربرین در تنظیم آستروسیتهای Gfap+ ناحیه هیپوکمپ موشهای صحرایی دیابتی شده با استرپتوزوتوسین
Background: Diabetes mellitus increases the risk of central nervous system (CNS) disorders such as stroke, seizures, dementia, and cognitive impairment. Berberine, a natural isoquinolne alkaloid, is reported to exhibit beneficial effect in various neurodegenerative and neuropsychiatric disorders. Moreover astrocytes are proving critical for normal CNS function, and alterations in their activity...
full textMy Resources
Journal title
volume 66 issue None
pages 682- 687
publication date 2008-12
By following a journal you will be notified via email when a new issue of this journal is published.
No Keywords
Hosted on Doprax cloud platform doprax.com
copyright © 2015-2023